ADAPTIL® Diffuser Refill for use with ADAPTIL® Diffuser device (132112), sold separately. ADAPTIL® Refills and Diffusers (sold separately) are designed to provide constant calming and comfort at home. Each refill lasts up to 30 days. ADAPTIL® is a synthetic copy of the natural appeasing pheromone mother dogs emit to comfort and reassure their puppies. It is clinically proven to help increase focus during training and reduce stress in puppies and adult dogs that can lead to unwanted behaviours.